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Neural cell engraftment therapy for sporadic Creutzfeldt-Jakob disease restores neuroelectrophysiological parameters in a cerebral organoid model

BACKGROUND: Sporadic Creutzfeldt-Jakob disease (sCJD), the most common human prion disease, is a fatal neurodegenerative disease with currently no treatment options. Stem cell therapy for neurodegenerative diseases is emerging as a possible treatment option. However, while there are a few clinical t...

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Detalles Bibliográficos
Autores principales: Williams, Katie, Foliaki, Simote T., Race, Brent, Smith, Anna, Thomas, Tina, Groveman, Bradley R., Haigh, Cathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696693/
https://www.ncbi.nlm.nih.gov/pubmed/38049877
http://dx.doi.org/10.1186/s13287-023-03591-2