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Neural cell engraftment therapy for sporadic Creutzfeldt-Jakob disease restores neuroelectrophysiological parameters in a cerebral organoid model
BACKGROUND: Sporadic Creutzfeldt-Jakob disease (sCJD), the most common human prion disease, is a fatal neurodegenerative disease with currently no treatment options. Stem cell therapy for neurodegenerative diseases is emerging as a possible treatment option. However, while there are a few clinical t...
Autores principales: | Williams, Katie, Foliaki, Simote T., Race, Brent, Smith, Anna, Thomas, Tina, Groveman, Bradley R., Haigh, Cathryn L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696693/ https://www.ncbi.nlm.nih.gov/pubmed/38049877 http://dx.doi.org/10.1186/s13287-023-03591-2 |
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