Integration of datasets for individual prediction of DNA methylation-based biomarkers

BACKGROUND: Epigenetic scores (EpiScores) can provide biomarkers of lifestyle and disease risk. Projecting new datasets onto a reference panel is challenging due to separation of technical and biological variation with array data. Normalisation can standardise data distributions but may also remove...

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Detalles Bibliográficos
Autores principales: Merzbacher, Charlotte, Ryan, Barry, Goldsborough, Thibaut, Hillary, Robert F., Campbell, Archie, Murphy, Lee, McIntosh, Andrew M., Liewald, David, Harris, Sarah E., McRae, Allan F., Cox, Simon R., Cannings, Timothy I., Vallejos, Catalina A., McCartney, Daniel L., Marioni, Riccardo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696831/
http://dx.doi.org/10.1186/s13059-023-03114-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696831/
http://dx.doi.org/10.1186/s13059-023-03114-5

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