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A large-scale genomically predicted protein mass database enables rapid and broad-spectrum identification of bacterial and archaeal isolates by mass spectrometry

MALDI-TOF MS-based microbial identification relies on reference spectral libraries, which limits the screening of diverse isolates, including uncultured lineages. We present a new strategy for broad-spectrum identification of bacterial and archaeal isolates by MALDI-TOF MS using a large-scale databa...

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Detalles Bibliográficos
Autores principales: Sekiguchi, Yuji, Teramoto, Kanae, Tourlousse, Dieter M., Ohashi, Akiko, Hamajima, Mayu, Miura, Daisuke, Yamada, Yoshihiro, Iwamoto, Shinichi, Tanaka, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696839/
https://www.ncbi.nlm.nih.gov/pubmed/38049850
http://dx.doi.org/10.1186/s13059-023-03096-4