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SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation

Reissner’s fiber (RF) is an extracellular polymer comprising the large monomeric protein SCO-spondin (SSPO) secreted by the subcommissural organ (SCO) that extends through cerebrospinal fluid (CSF)-filled ventricles into the central canal of the spinal cord. In zebrafish, RF and CSF-contacting neuro...

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Detalles Bibliográficos
Autores principales: Xu, Huixin, Dugué, Guillaume P., Cantaut-Belarif, Yasmine, Lejeune, François-Xavier, Gupta, Suhasini, Wyart, Claire, Lehtinen, Maria K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696872/
https://www.ncbi.nlm.nih.gov/pubmed/38049798
http://dx.doi.org/10.1186/s12987-023-00491-8