Cargando…
SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation
Reissner’s fiber (RF) is an extracellular polymer comprising the large monomeric protein SCO-spondin (SSPO) secreted by the subcommissural organ (SCO) that extends through cerebrospinal fluid (CSF)-filled ventricles into the central canal of the spinal cord. In zebrafish, RF and CSF-contacting neuro...
Autores principales: | Xu, Huixin, Dugué, Guillaume P., Cantaut-Belarif, Yasmine, Lejeune, François-Xavier, Gupta, Suhasini, Wyart, Claire, Lehtinen, Maria K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696872/ https://www.ncbi.nlm.nih.gov/pubmed/38049798 http://dx.doi.org/10.1186/s12987-023-00491-8 |
Ejemplares similares
-
SCO-spondin oligopeptide inhibits angiogenesis in glioblastoma
por: Bibes, Romain, et al.
Publicado: (2017) -
The Reissner Fiber in the Cerebrospinal Fluid Controls Morphogenesis of the Body Axis
por: Cantaut-Belarif, Yasmine, et al.
Publicado: (2018) -
Loss of CSF-contacting neuron sensory function is associated with a hyper-kyphosis of the spine reminiscent of Scheuermann’s disease
por: Marie-Hardy, Laura, et al.
Publicado: (2023) -
The Reissner fiber under tension in vivo shows dynamic interaction with ciliated cells contacting the cerebrospinal fluid
por: Bellegarda, Celine, et al.
Publicado: (2023) -
SCO-spondin, a giant matricellular protein that regulates cerebrospinal fluid activity
por: Sepúlveda, Vania, et al.
Publicado: (2021)