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High-capacity sample multiplexing for single cell chromatin accessibility profiling

Single-cell chromatin accessibility has emerged as a powerful means of understanding the epigenetic landscape of diverse tissues and cell types, but profiling cells from many independent specimens is challenging and costly. Here we describe a novel approach, sciPlex-ATAC-seq, which uses unmodified D...

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Detalles Bibliográficos
Autores principales: Booth, Gregory T., Daza, Riza M., Srivatsan, Sanjay R., McFaline-Figueroa, José L., Gladden, Rula Green, Mullen, Andrew C., Furlan, Scott N., Shendure, Jay, Trapnell, Cole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696879/
https://www.ncbi.nlm.nih.gov/pubmed/38049719
http://dx.doi.org/10.1186/s12864-023-09832-1