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Whole-brain modeling of the differential influences of amyloid-beta and tau in Alzheimer’s disease
BACKGROUND: Alzheimer’s disease is a neurodegenerative condition associated with the accumulation of two misfolded proteins, amyloid-beta (A[Formula: see text] ) and tau. We study their effect on neuronal activity, with the aim of assessing their individual and combined impact. METHODS: We use a who...
Autores principales: | Patow, Gustavo, Stefanovski, Leon, Ritter, Petra, Deco, Gustavo, Kobeleva, Xenia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696890/ http://dx.doi.org/10.1186/s13195-023-01349-9 |
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