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An in vitro investigation of the effects of urolithins A and B on low-density lipoprotein uptake and its regulatory genes

INTRODUCTION: This study aimed to evaluate the possible role of urolithin A (UA) and urolithin B (UB) on the mRNA expression levels of LDL receptor (LDLR) and PSCK9 genes, and also of the uptake of LDL particles in HepG2 cells. MATERIAL AND METHODS: The potential role of UA and UB on the induction o...

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Detalles Bibliográficos
Autores principales: Ganjali, Shiva, Matbou Riahi, Maryam, Mahboobnia, Khadijeh, Iranshahy, Milad, Banach, Maciej, Jangjoo, Ali, Ashari, Sorour, Tayarani-Najaran, Zahra, Sahebkar, Amirhossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696988/
http://dx.doi.org/10.5114/aoms/168120