Diabetic Müller-Glial-Cell-Specific Il6ra Knockout Mice Exhibit Accelerated Retinal Functional Decline and Thinning of the Inner Nuclear Layer

PURPOSE: Interleukin-6 (IL-6) is implicated in the pathology of diabetic retinopathy (DR). IL-6 trans-signaling via soluble IL-6 receptor (IL-6R) is primarily responsible for its pro-inflammatory functions, whereas cis-signaling via membrane-bound IL-6R is anti-inflammatory. Using a Müller-glial-cel...

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Detalles Bibliográficos
Autores principales: Glass, Joshua, Robinson, Rebekah L., Greenway, Grace, Jones, Garrett, Sharma, Shruti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697173/
https://www.ncbi.nlm.nih.gov/pubmed/38038619
http://dx.doi.org/10.1167/iovs.64.15.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697173/
https://www.ncbi.nlm.nih.gov/pubmed/38038619
http://dx.doi.org/10.1167/iovs.64.15.1

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