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SIRT3 Activator Honokiol Inhibits Th17 Cell Differentiation and Alleviates Colitis

BACKGROUND: Honokiol (HKL), a natural extract of the bark of the magnolia tree and an activator of the mitochondrial protein sirtuin-3 (SIRT3), has been proposed to possess anti-inflammatory effects. This study investigated the inhibitory effects of HKL on T helper (Th) 17 cell differentiation in co...

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Detalles Bibliográficos
Autores principales: Chen, Xiaotian, Zhang, Mingming, Zhou, Fan, Gu, Zhengrong, Li, Yuan, Yu, Ting, Peng, Chunyan, Zhou, Lixing, Li, Xiangrui, Zhu, Dandan, Zhang, Xiaoqi, Yu, Chenggong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697418/
https://www.ncbi.nlm.nih.gov/pubmed/37335900
http://dx.doi.org/10.1093/ibd/izad099