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Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food

The increasing prevalence of food allergies has been linked to reduced commensal microbial diversity. In this article, we describe two features of allergy-protective Clostridia that contribute to their beneficial effects. Some Clostridial taxa bear flagella (a ligand for TLR5) and produce indole (a...

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Detalles Bibliográficos
Autores principales: Kemter, Andrea M., Patry, Robert T., Arnold, Jack, Hesser, Lauren A., Campbell, Evelyn, Ionescu, Edward, Mimee, Mark, Wang, Shan, Nagler, Cathryn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697505/
https://www.ncbi.nlm.nih.gov/pubmed/37742185
http://dx.doi.org/10.1016/j.celrep.2023.113153