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L1 retrotransposon-mediated stable gene silencing

RNA interference (RNAi) is widely used for functional studies and has been proposed as a potential therapeutic agent. Current RNAi systems are largely efficient, but have limitations including transient effect, the need for viral handling and potential insertional mutations. Here, we describe a simp...

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Detalles Bibliográficos
Autores principales: Yang, Nuo, Zhang, Lin, Kazazian, Haig H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1072808/
https://www.ncbi.nlm.nih.gov/pubmed/15800208
http://dx.doi.org/10.1093/nar/gni056