Cargando…

An Unbiased Cell Morphology–Based Screen for New, Biologically Active Small Molecules

We have implemented an unbiased cell morphology–based screen to identify small-molecule modulators of cellular processes using the Cytometrix (TM) automated imaging and analysis system. This assay format provides unbiased analysis of morphological effects induced by small molecules by capturing phen...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanaka, Masahiro, Bateman, Raynard, Rauh, Daniel, Vaisberg, Eugeni, Ramachandani, Shyam, Zhang, Chao, Hansen, Kirk C, Burlingame, Alma L, Trautman, Jay K, Shokat, Kevan M, Adams, Cynthia L
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1073692/
https://www.ncbi.nlm.nih.gov/pubmed/15799708
http://dx.doi.org/10.1371/journal.pbio.0030128