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An Unbiased Cell Morphology–Based Screen for New, Biologically Active Small Molecules
We have implemented an unbiased cell morphology–based screen to identify small-molecule modulators of cellular processes using the Cytometrix (TM) automated imaging and analysis system. This assay format provides unbiased analysis of morphological effects induced by small molecules by capturing phen...
Autores principales: | Tanaka, Masahiro, Bateman, Raynard, Rauh, Daniel, Vaisberg, Eugeni, Ramachandani, Shyam, Zhang, Chao, Hansen, Kirk C, Burlingame, Alma L, Trautman, Jay K, Shokat, Kevan M, Adams, Cynthia L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1073692/ https://www.ncbi.nlm.nih.gov/pubmed/15799708 http://dx.doi.org/10.1371/journal.pbio.0030128 |
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