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An Unbiased Cell Morphology–Based Screen for New, Biologically Active Small Molecules

We have implemented an unbiased cell morphology–based screen to identify small-molecule modulators of cellular processes using the Cytometrix (TM) automated imaging and analysis system. This assay format provides unbiased analysis of morphological effects induced by small molecules by capturing phen...

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Detalles Bibliográficos
Autores principales: Tanaka, Masahiro, Bateman, Raynard, Rauh, Daniel, Vaisberg, Eugeni, Ramachandani, Shyam, Zhang, Chao, Hansen, Kirk C, Burlingame, Alma L, Trautman, Jay K, Shokat, Kevan M, Adams, Cynthia L
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1073692/
https://www.ncbi.nlm.nih.gov/pubmed/15799708
http://dx.doi.org/10.1371/journal.pbio.0030128

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