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Structure of HinP1I endonuclease reveals a striking similarity to the monomeric restriction enzyme MspI

HinP1I, a type II restriction endonuclease, recognizes and cleaves a palindromic tetranucleotide sequence (G↓CGC) in double-stranded DNA, producing 2 nt 5′ overhanging ends. Here, we report the structure of HinP1I crystallized as one protein monomer in the crystallographic asymmetric unit. HinP1I di...

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Detalles Bibliográficos
Autores principales: Yang, Zhe, Horton, John R., Maunus, Robert, Wilson, Geoffrey G., Roberts, Richard J., Cheng, Xiaodong
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1074309/
https://www.ncbi.nlm.nih.gov/pubmed/15805123
http://dx.doi.org/10.1093/nar/gki337