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Sensitization of TRPV1 by EP(1 )and IP reveals peripheral nociceptive mechanism of prostaglandins

Prostaglandin E(2 )(PGE(2)) and prostaglandin I(2 )(PGI(2)) are major inflammatory mediators that play important roles in pain sensation and hyperalgesia. The role of their receptors (EP and IP, respectively) in inflammation has been well documented, although the EP receptor subtypes involved in thi...

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Detalles Bibliográficos
Autores principales: Moriyama, Tomoko, Higashi, Tomohiro, Togashi, Kazuya, Iida, Tohko, Segi, Eri, Sugimoto, Yukihiko, Tominaga, Tomoko, Narumiya, Shuh, Tominaga, Makoto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1074353/
https://www.ncbi.nlm.nih.gov/pubmed/15813989
http://dx.doi.org/10.1186/1744-8069-1-3