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tRNA-linked molecular beacons for imaging mRNAs in the cytoplasm of living cells
When oligonucleotide probes are microinjected into cells to image the distribution of RNAs, they are rapidly sequestered into the nucleus. As a result, it is difficult to detect mRNAs in the cytoplasm of living cells. We were able to overcome this process by attaching tRNA transcripts to the probes....
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1074395/ https://www.ncbi.nlm.nih.gov/pubmed/15809226 http://dx.doi.org/10.1093/nar/gki302 |