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Pre-organized structure of viral DNA at the binding-processing site of HIV-1 integrase

The integration of the human immunodeficiency virus type 1 DNA into the host cell genome is catalysed by the viral integrase (IN). The reaction consists of a 3′-processing [dinucleotide released from each 3′ end of the viral long terminal repeat (LTR)] followed by a strand transfer (insertion of the...

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Detalles Bibliográficos
Autores principales: Renisio, Jean-Guillaume, Cosquer, Sylvain, Cherrak, Ilham, Antri, Saïd El, Mauffret, Olivier, Fermandjian, Serge
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1074723/
https://www.ncbi.nlm.nih.gov/pubmed/15814814
http://dx.doi.org/10.1093/nar/gki346