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Human Ku70/80 interacts directly with hTR, the RNA component of human telomerase

Maintenance of telomere integrity requires the dynamic interplay between telomerase, telomere-associated proteins and DNA repair proteins. These interactions are vital to suppress DNA damage responses and changes in chromosome dynamics that can result in aneuploidy or other transforming aberrations....

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Detalles Bibliográficos
Autores principales: Ting, Nicholas S. Y., Yu, Yaping, Pohorelic, Brant, Lees-Miller, Susan P., Beattie, Tara L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1075923/
https://www.ncbi.nlm.nih.gov/pubmed/15824061
http://dx.doi.org/10.1093/nar/gki342