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A Combinatorial Code for Splicing Silencing: UAGG and GGGG Motifs

Alternative pre-mRNA splicing is widely used to regulate gene expression by tuning the levels of tissue-specific mRNA isoforms. Few regulatory mechanisms are understood at the level of combinatorial control despite numerous sequences, distinct from splice sites, that have been shown to play roles in...

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Detalles Bibliográficos
Autores principales: Han, Kyoungha, Yeo, Gene, An, Ping, Burge, Christopher B, Grabowski, Paula J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079783/
https://www.ncbi.nlm.nih.gov/pubmed/15828859
http://dx.doi.org/10.1371/journal.pbio.0030158