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A Combinatorial Code for Splicing Silencing: UAGG and GGGG Motifs
Alternative pre-mRNA splicing is widely used to regulate gene expression by tuning the levels of tissue-specific mRNA isoforms. Few regulatory mechanisms are understood at the level of combinatorial control despite numerous sequences, distinct from splice sites, that have been shown to play roles in...
Autores principales: | Han, Kyoungha, Yeo, Gene, An, Ping, Burge, Christopher B, Grabowski, Paula J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079783/ https://www.ncbi.nlm.nih.gov/pubmed/15828859 http://dx.doi.org/10.1371/journal.pbio.0030158 |
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