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Genotyping DNA pools on microarrays: Tackling the QTL problem of large samples and large numbers of SNPs

BACKGROUND: Quantitative trait locus (QTL) theory predicts that genetic influence on complex traits involves multiple genes of small effect size. To detect QTL associations of small effect size, large samples and systematic screens of thousands of DNA markers are required. An efficient solution is t...

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Detalles Bibliográficos
Autores principales: Meaburn, Emma, Butcher, Lee M, Liu, Lin, Fernandes, Cathy, Hansen, Valerie, Al-Chalabi, Ammar, Plomin, Robert, Craig, Ian, Schalkwyk, Leonard C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079828/
https://www.ncbi.nlm.nih.gov/pubmed/15811185
http://dx.doi.org/10.1186/1471-2164-6-52