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Genotyping DNA pools on microarrays: Tackling the QTL problem of large samples and large numbers of SNPs
BACKGROUND: Quantitative trait locus (QTL) theory predicts that genetic influence on complex traits involves multiple genes of small effect size. To detect QTL associations of small effect size, large samples and systematic screens of thousands of DNA markers are required. An efficient solution is t...
Autores principales: | Meaburn, Emma, Butcher, Lee M, Liu, Lin, Fernandes, Cathy, Hansen, Valerie, Al-Chalabi, Ammar, Plomin, Robert, Craig, Ian, Schalkwyk, Leonard C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079828/ https://www.ncbi.nlm.nih.gov/pubmed/15811185 http://dx.doi.org/10.1186/1471-2164-6-52 |
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