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Polymorphism screening and haplotype analysis of the tryptophan hydroxylase gene (TPH1) and association with bipolar affective disorder in Taiwan

BACKGROUND: Disturbances in serotonin neurotransmission are implicated in the etiology of many psychiatric disorders, including bipolar affective disorder (BPD). The tryptophan hydroxylase gene (TPH), which codes for the enzyme catalyzing the rate-limiting step in serotonin biosynthetic pathway, is...

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Detalles Bibliográficos
Autores principales: Lai, Te-Jen, Wu, Chia-Yen, Tsai, Hsu-Wen, Lin, Yi-Mei J, Sun, H Sunny
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079843/
https://www.ncbi.nlm.nih.gov/pubmed/15799788
http://dx.doi.org/10.1186/1471-2350-6-14