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A polymorphism at codon 31 of gene p21 is not associated with primary open angle glaucoma in Caucasians

BACKGROUND: Primary open angle glaucoma (POAG) is considered to be a neurodegenerative optic neuropathy, in which cell death occurs by apoptosis. p21, is an important protective component of the apoptotic pathway, regulating cellular arrest in the presence of DNA damage. An unstable or altered p21 p...

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Detalles Bibliográficos
Autores principales: Ressiniotis, Thomas, Griffiths, Philip G, Keers, Sharon M, Chinnery, Patrick F, Birch, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079871/
https://www.ncbi.nlm.nih.gov/pubmed/15807891
http://dx.doi.org/10.1186/1471-2415-5-5