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Detecting DNA-binding helix–turn–helix structural motifs using sequence and structure information

In this work, we analyse the potential for using structural knowledge to improve the detection of the DNA-binding helix–turn–helix (HTH) motif from sequence. Starting from a set of DNA-binding protein structures that include a functional HTH motif and have no apparent sequence similarity to each oth...

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Detalles Bibliográficos
Autores principales: Pellegrini-Calace, Marialuisa, Thornton, Janet M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079965/
https://www.ncbi.nlm.nih.gov/pubmed/15831786
http://dx.doi.org/10.1093/nar/gki349