Eukaryotic RNases H1 act processively by interactions through the duplex RNA-binding domain

Ribonucleases H have mostly been implicated in eliminating short RNA primers used for initiation of lagging strand DNA synthesis. Escherichia coli RNase HI cleaves these RNA–DNA hybrids in a distributive manner. We report here that eukaryotic RNases H1 have evolved to be processive enzymes by attach...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaidamakov, Sergei A., Gorshkova, Inna I., Schuck, Peter, Steinbach, Peter J., Yamada, Hirofumi, Crouch, Robert J., Cerritelli, Susana M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079969/
https://www.ncbi.nlm.nih.gov/pubmed/15831789
http://dx.doi.org/10.1093/nar/gki510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079969/
https://www.ncbi.nlm.nih.gov/pubmed/15831789
http://dx.doi.org/10.1093/nar/gki510

Ejemplares similares