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Eukaryotic RNases H1 act processively by interactions through the duplex RNA-binding domain

Ribonucleases H have mostly been implicated in eliminating short RNA primers used for initiation of lagging strand DNA synthesis. Escherichia coli RNase HI cleaves these RNA–DNA hybrids in a distributive manner. We report here that eukaryotic RNases H1 have evolved to be processive enzymes by attach...

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Detalles Bibliográficos
Autores principales:	Gaidamakov, Sergei A., Gorshkova, Inna I., Schuck, Peter, Steinbach, Peter J., Yamada, Hirofumi, Crouch, Robert J., Cerritelli, Susana M.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079969/ https://www.ncbi.nlm.nih.gov/pubmed/15831789 http://dx.doi.org/10.1093/nar/gki510

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