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APE1-dependent repair of DNA single-strand breaks containing 3′-end 8-oxoguanine

DNA single-strand breaks containing 3′-8-oxoguanine (3′-8-oxoG) ends can arise as a consequence of ionizing radiation and as a result of DNA polymerase infidelity by misincorporation of 8-oxodGMP. In this study we examined the mechanism of repair of 3′-8-oxoG within a single-strand break using purif...

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Detalles Bibliográficos
Autores principales: Parsons, Jason L., Dianova, Irina I., Dianov, Grigory L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079973/
https://www.ncbi.nlm.nih.gov/pubmed/15831793
http://dx.doi.org/10.1093/nar/gki518