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Analysis of the CCR3 promoter reveals a regulatory region in exon 1 that binds GATA-1

BACKGROUND: CC Chemokine Receptor 3 (CCR3), the major chemokine receptor expressed on eosinophils, binds promiscuously to several ligands including eotaxins 1, 2, and 3. Even though the only cells that consistently accumulate following eotaxin administration in vivo are myeloid cells (primarily eosi...

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Detalles Bibliográficos
Autores principales: Zimmermann, Nives, Colyer, Jessica L, Koch, Laura E, Rothenberg, Marc E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1080127/
https://www.ncbi.nlm.nih.gov/pubmed/15807893
http://dx.doi.org/10.1186/1471-2172-6-7