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The de novo methylation activity of Dnmt3a is distinctly different than that of Dnmt1

BACKGROUND: Though Dnmt1 is considered the primary maintenance methyltransferase and Dnmt3a and Dnmt3b are considered de novo methyltransferases in mammals, these three enzymes may work together in maintaining as well as establishing DNA methylation patterns. It has been proposed that Dnmt1 may carr...

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Detalles Bibliográficos
Autor principal: Hsieh, Chih-Lin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1084342/
https://www.ncbi.nlm.nih.gov/pubmed/15799776
http://dx.doi.org/10.1186/1471-2091-6-6