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The de novo methylation activity of Dnmt3a is distinctly different than that of Dnmt1
BACKGROUND: Though Dnmt1 is considered the primary maintenance methyltransferase and Dnmt3a and Dnmt3b are considered de novo methyltransferases in mammals, these three enzymes may work together in maintaining as well as establishing DNA methylation patterns. It has been proposed that Dnmt1 may carr...
Autor principal: | Hsieh, Chih-Lin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1084342/ https://www.ncbi.nlm.nih.gov/pubmed/15799776 http://dx.doi.org/10.1186/1471-2091-6-6 |
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