Deficiency in type 1 insulin-like growth factor receptor in mice protects against oxygen-induced lung injury

BACKGROUND: Cellular responses to aging and oxidative stress are regulated by type 1 insulin-like growth factor receptor (IGF-1R). Oxidant injury, which is implicated in the pathophysiology of a number of respiratory diseases, acutely upregulates IGF-1R expression in the lung. This led us to suspect...

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Detalles Bibliográficos
Autores principales: Ahamed, Karmene, Epaud, Ralph, Holzenberger, Martin, Bonora, Monique, Flejou, Jean-François, Puard, Julien, Clement, Annick, Henrion-Caude, Alexandra
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1084363/
https://www.ncbi.nlm.nih.gov/pubmed/15819984
http://dx.doi.org/10.1186/1465-9921-6-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1084363/
https://www.ncbi.nlm.nih.gov/pubmed/15819984
http://dx.doi.org/10.1186/1465-9921-6-31

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