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Deficiency in type 1 insulin-like growth factor receptor in mice protects against oxygen-induced lung injury

BACKGROUND: Cellular responses to aging and oxidative stress are regulated by type 1 insulin-like growth factor receptor (IGF-1R). Oxidant injury, which is implicated in the pathophysiology of a number of respiratory diseases, acutely upregulates IGF-1R expression in the lung. This led us to suspect...

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Detalles Bibliográficos
Autores principales:	Ahamed, Karmene, Epaud, Ralph, Holzenberger, Martin, Bonora, Monique, Flejou, Jean-François, Puard, Julien, Clement, Annick, Henrion-Caude, Alexandra
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1084363/ https://www.ncbi.nlm.nih.gov/pubmed/15819984 http://dx.doi.org/10.1186/1465-9921-6-31

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