The C-terminal subunit of artificially truncated human cathepsin B mediates its nuclear targeting and contributes to cell viability

BACKGROUND: Splicing variants of human cathepsinB primary transcripts (CB(-2,3)) result in an expression product product which lacks the signal peptide and parts of the propeptide. This naturally truncated Δ(51)CB is thus unable to follow the regular CB processing and sorting pathway. It is addresse...

Descripción completa

Detalles Bibliográficos
Autores principales: Bestvater, Felix, Dallner, Claudia, Spiess, Eberhard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087480/
https://www.ncbi.nlm.nih.gov/pubmed/15807897
http://dx.doi.org/10.1186/1471-2121-6-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087480/
https://www.ncbi.nlm.nih.gov/pubmed/15807897
http://dx.doi.org/10.1186/1471-2121-6-16

Ejemplares similares