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The C-terminal subunit of artificially truncated human cathepsin B mediates its nuclear targeting and contributes to cell viability
BACKGROUND: Splicing variants of human cathepsinB primary transcripts (CB(-2,3)) result in an expression product product which lacks the signal peptide and parts of the propeptide. This naturally truncated Δ(51)CB is thus unable to follow the regular CB processing and sorting pathway. It is addresse...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087480/ https://www.ncbi.nlm.nih.gov/pubmed/15807897 http://dx.doi.org/10.1186/1471-2121-6-16 |