Cargando…

Cyclohexenyl nucleic acids: conformationally flexible oligonucleotides

Cyclohexenyl nucleic acid (CeNA) is a nucleic acid mimic, where the (deoxy)ribose sugar has been replaced by cyclohexenyl moieties. In order to study the conformation of cyclohexenyl nucleosides by NMR, the HexRot program was developed to calculate conformations from scalar coupling constants of cyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Nauwelaerts, Koen, Lescrinier, Eveline, Sclep, Gert, Herdewijn, Piet
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087899/
https://www.ncbi.nlm.nih.gov/pubmed/15863723
http://dx.doi.org/10.1093/nar/gki538