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Studies on Escherichia coli RNase P RNA with Zn(2+) as the catalytic cofactor
We demonstrate, for the first time, catalysis by Escherichia coli ribonuclease P (RNase P) RNA with Zn(2+) as the sole divalent metal ion cofactor in the presence of ammonium, but not sodium or potassium salts. Hill analysis suggests a role for two or more Zn(2+) ions in catalysis. Whereas Zn(2+) de...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088067/ https://www.ncbi.nlm.nih.gov/pubmed/15867194 http://dx.doi.org/10.1093/nar/gki540 |