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Inhibition of Mutation and Combating the Evolution of Antibiotic Resistance

The emergence of drug-resistant bacteria poses a serious threat to human health. In the case of several antibiotics, including those of the quinolone and rifamycin classes, bacteria rapidly acquire resistance through mutation of chromosomal genes during therapy. In this work, we show that preventing...

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Detalles Bibliográficos
Autores principales: Cirz, Ryan T, Chin, Jodie K, Andes, David R, de Crécy-Lagard, Valérie, Craig, William A, Romesberg, Floyd E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088971/
https://www.ncbi.nlm.nih.gov/pubmed/15869329
http://dx.doi.org/10.1371/journal.pbio.0030176