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Inhibition of Mutation and Combating the Evolution of Antibiotic Resistance
The emergence of drug-resistant bacteria poses a serious threat to human health. In the case of several antibiotics, including those of the quinolone and rifamycin classes, bacteria rapidly acquire resistance through mutation of chromosomal genes during therapy. In this work, we show that preventing...
Autores principales: | Cirz, Ryan T, Chin, Jodie K, Andes, David R, de Crécy-Lagard, Valérie, Craig, William A, Romesberg, Floyd E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088971/ https://www.ncbi.nlm.nih.gov/pubmed/15869329 http://dx.doi.org/10.1371/journal.pbio.0030176 |
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