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Production of viral vectors using recombinase-mediated cassette exchange

DNA viruses are often used as vectors for foreign gene expression, but large DNA region from cloned or authentic viral genomes must usually be handled to generate viral vectors. Here, we present a unique system for generating adenoviral vectors by directly substituting a gene of interest in a small...

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Detalles Bibliográficos
Autores principales: Nakano, Masakazu, Odaka, Kazuhiko, Takahashi, Yuzuka, Ishimura, Masakazu, Saito, Izumu, Kanegae, Yumi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1090444/
https://www.ncbi.nlm.nih.gov/pubmed/15879348
http://dx.doi.org/10.1093/nar/gni074