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Molecular beacons with a homo-DNA stem: improving target selectivity
Molecular beacons (MBs) are stem–loop DNA probes used for identifying and reporting the presence and localization of nucleic acid targets in vitro and in vivo via target-dependent dequenching of fluorescence. A drawback of conventional MB design is present in the stem sequence that is necessary to k...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1090445/ https://www.ncbi.nlm.nih.gov/pubmed/15879349 http://dx.doi.org/10.1093/nar/gni076 |