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Molecular beacons with a homo-DNA stem: improving target selectivity

Molecular beacons (MBs) are stem–loop DNA probes used for identifying and reporting the presence and localization of nucleic acid targets in vitro and in vivo via target-dependent dequenching of fluorescence. A drawback of conventional MB design is present in the stem sequence that is necessary to k...

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Detalles Bibliográficos
Autores principales: Crey-Desbiolles, Caroline, Ahn, Dae-Ro, Leumann, Christian J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1090445/
https://www.ncbi.nlm.nih.gov/pubmed/15879349
http://dx.doi.org/10.1093/nar/gni076