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Trapping of normal EB1 ligands in aggresomes formed by an EB1 deletion mutant

BACKGROUND: EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and the p150glued subunit of dynactin. We previously reported that an EB1 deletion mutant that retains both of these interactions but does not directly associate with microtubules (EB1-ΔN2-G...

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Detalles Bibliográficos
Autores principales: Riess, Nick P, Milward, Kelly, Lee, Tracy, Adams, Matthew, Askham, Jon M, Morrison, Ewan E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1090566/
https://www.ncbi.nlm.nih.gov/pubmed/15813965
http://dx.doi.org/10.1186/1471-2121-6-17