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Comparison of amplification enzymes for Hepatitis C Virus quasispecies analysis

BACKGROUND: Hepatitis C virus (HCV) circulates as quasispecies (QS), whose evolution is associated with pathogenesis. Previous studies have suggested that the use of thermostable polymerases without proofreading function may contribute to inaccurate assessment of HCV QS. In this report, we compared...

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Detalles Bibliográficos
Autores principales: Polyak, Stephen J, Sullivan, Daniel G, Austin, Michael A, Dai, James Y, Shuhart, Margaret C, Lindsay, Karen L, Bonkovsky, Herbert L, Di Bisceglie, Adrian M, Lee, William M, Morishima, Chihiro, Gretch, David R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1090623/
https://www.ncbi.nlm.nih.gov/pubmed/15847697
http://dx.doi.org/10.1186/1743-422X-2-41