Molecular haplotyping by linking emulsion PCR: analysis of paraoxonase 1 haplotypes and phenotypes

Linking emulsion PCR (LE-PCR) enables formation of minichromosomes preserving phase information of two polymorphic loci, hence the haplotype. Emulsion PCR confines two amplicons of two linked polymorphic sites on a single template molecule to one aqueous-phase droplet. Linking PCR uses biotinylated,...

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Detalles Bibliográficos
Autores principales: Wetmur, James G., Kumar, Madhu, Zhang, Li, Palomeque, Caroline, Wallenstein, Sylvan, Chen, Jia
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1092276/
https://www.ncbi.nlm.nih.gov/pubmed/15886392
http://dx.doi.org/10.1093/nar/gki556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1092276/
https://www.ncbi.nlm.nih.gov/pubmed/15886392
http://dx.doi.org/10.1093/nar/gki556

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