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Molecular haplotyping by linking emulsion PCR: analysis of paraoxonase 1 haplotypes and phenotypes
Linking emulsion PCR (LE-PCR) enables formation of minichromosomes preserving phase information of two polymorphic loci, hence the haplotype. Emulsion PCR confines two amplicons of two linked polymorphic sites on a single template molecule to one aqueous-phase droplet. Linking PCR uses biotinylated,...
Autores principales: | Wetmur, James G., Kumar, Madhu, Zhang, Li, Palomeque, Caroline, Wallenstein, Sylvan, Chen, Jia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1092276/ https://www.ncbi.nlm.nih.gov/pubmed/15886392 http://dx.doi.org/10.1093/nar/gki556 |
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