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The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions

The transcription factor Pax6 is essential for the development of the eyes and the central nervous system of vertebrates and invertebrates. Pax6 contains two DNA-binding domains; an N-terminal paired domain and a centrally located homeodomain. We have previously shown that the vertebrate paired-less...

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Detalles Bibliográficos
Autores principales: Bruun, Jack-Ansgar, Thomassen, Ernst Ivan Simon, Kristiansen, Kurt, Tylden, Garth, Holm, Turid, Mikkola, Ingvild, Bjørkøy, Geir, Johansen, Terje
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1092277/
https://www.ncbi.nlm.nih.gov/pubmed/15886395
http://dx.doi.org/10.1093/nar/gki562