DNA-tension dependence of restriction enzyme activity reveals mechanochemical properties of the reaction pathway

Type II restriction endonucleases protect bacteria against phage infections by cleaving recognition sites on foreign double-stranded DNA (dsDNA) with extraordinary specificity. This capability arises primarily from large conformational changes in enzyme and/or DNA upon target sequence recognition. I...

Descripción completa

Detalles Bibliográficos
Autores principales: van den Broek, Bram, Noom, Maarten C., Wuite, Gijs J. L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1092278/
https://www.ncbi.nlm.nih.gov/pubmed/15886396
http://dx.doi.org/10.1093/nar/gki565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1092278/
https://www.ncbi.nlm.nih.gov/pubmed/15886396
http://dx.doi.org/10.1093/nar/gki565

Ejemplares similares