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DNA-tension dependence of restriction enzyme activity reveals mechanochemical properties of the reaction pathway
Type II restriction endonucleases protect bacteria against phage infections by cleaving recognition sites on foreign double-stranded DNA (dsDNA) with extraordinary specificity. This capability arises primarily from large conformational changes in enzyme and/or DNA upon target sequence recognition. I...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1092278/ https://www.ncbi.nlm.nih.gov/pubmed/15886396 http://dx.doi.org/10.1093/nar/gki565 |